Vitamin C ‘as Effective as Exercise’ at Improving Vascular Tone

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By Julie Fidler

Vitamin C may mimic some of the effects of exercise in overweight and obese individuals. [1]

The protein endothelin-1 (ET-1) has a constricting action on small blood vessels. This activity is increased in overweight and obese individuals, making small blood vessels more prone to constrict and less able to handle blood flow demand, increasing the risk of vascular disease. At the start of the study, all of the participants had impaired vascular tone.

Caitlin Dow, PhD, postdoctoral research fellow at the University of Colorado, Boulder, and colleagues followed 35 sedentary, overweight or obese adults throughout three months. Twenty participants …read more

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