By Julie Fidler
The U.S. Food and Drug Administration (FDA) confirms the popular Johnson & Johnson (J&J) diabetes drug Invokana (Invokamet, Invokamet XR) increases the risk of foot and leg amputations in people with Type 2 diabetes. [1]
The results of 2 clinical trials showed leg and foot amputations occurred about twice as often in patients taking Invokana (generic name: canagliflozin) as those given a placebo, according to an announcement on the FDA’s website. [2]
The nation’s health watchdog says it is requiring that new warnings, including its most prominent Boxed Warning, be added to the Invokana label.
One of the clinical trials indicated that over …read more
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