Study: Antipsychotic Drugs Found to Shrink the Brains of Patients

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By Julie Fidler

The authors of a new study are warning that long-term use of antipsychotic drugs, used to treat schizophrenia, bipolar disorder, and other psychiatric illnesses, may negatively impact brain structure.

Dr. Antonio Vita, professor of psychiatry at the University of Brescia in Italy, and colleagues looked at how first- and second-generation antipsychotics affected the brains of 1,155 people with schizophrenia, and compared them with 911 healthy individuals. Scientists selected participants from 18 brain imaging studies.

The researchers found that schizophrenic patients treated with antipsychotics showed a progressive loss of gray matter in the brain, compared with the healthy controls. [1]

First-generation antipsychotics, …read more

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